Collagen banking e prevenzione della perdita di collagene
The Founder’s voice

Collagen banking: can you really store collagen for later?

Elisa Avalleof Elisa Avalle , founder of LeLang

6 min read

Collagen banking is the idea that you can build up collagen when you’re young to have a reserve later on. It’s a banking metaphor: deposit now, withdraw later.

The principle behind it is correct. The metaphor, however, describes something collagen doesn’t do.

Dermal collagen doesn’t work like a bank account: there’s no reserve to draw on, but rather a constant balance between synthesis and degradation. Your habits in your twenties really do matter, but not because they set something aside: they reduce the damage that accelerates degradation. The difference may seem subtle, but it changes everything about what makes sense to buy.

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Elisa Avalle, founder and CEO of LeLang Skin Care

Elisa Avalle · Founder and dermocosmetics specialist

This is the kind of case I most enjoy studying: real scientific data, poorly summarized once, then repeated for twenty years until the wrong version became the one everyone knows.

Langhe, September 20, 2026

The number everyone knows and few have checked

You’ll have read everywhere that you lose about 1% of your collagen every year from the age of 25. It’s the most frequently cited figure in cosmetics, appearing in product descriptions, videos, and newspaper articles.

I went looking for the primary source, and what I found is interesting. The strongest reference study on this topic is by Varani and colleagues, published in 2006 in the American Journal of Pathology. It measures collagen production in chronologically aged skin and reports a reduction in type I procollagen of about 75% in people over 80 compared with the 18-29 age group.

Notice the difference. The study compares two age extremes and measures an overall gap. It does not describe a linear decline of 1% every year. That 1% is a popular extrapolation: someone divided a total loss by the number of years and arrived at an annual rate that the source does not claim.

This isn’t a nitpicky distinction. A linear decline suggests that each year of loss is identical to the next, and therefore that there’s a window to protect at all costs. A difference measured between two extremes says something different and more useful: the process isn’t uniform, it depends heavily on cumulative exposure, and that leaves room for intervention.

What really happens in the dermis

Collagen is the main structural protein in the dermis, produced by fibroblasts. It is constantly being remodeled: it is synthesized and broken down by enzymes in a cycle that never stops.

With age, two things change at once. Fibroblasts produce less, and degradation increases. On top of that is the biggest factor of all: exposure to ultraviolet rays, which activates degradative enzymes and fragments the existing matrix. I described the full mechanism in my article on how collagen is lost.

That’s why the banking metaphor doesn’t hold up. There’s no warehouse; there’s a construction site that’s always open. What you can influence isn’t the amount deposited: it’s how quickly the site is damaged.

“You don’t deposit collagen. You avoid destroying it faster than necessary. It’s less glamorous, and much more achievable.”

The right principle inside the wrong metaphor

It would be wrong to dismiss collagen banking as a gimmick, because its core idea is sound: what you do at twenty-five affects the skin you’ll have at fifty. The literature agrees on this, and the evidence is robust.

The problem is that the label gets slapped on products that have little to do with the principle behind it. If “banking” means prevention, then the tools are familiar ones: daily sun protection, retinoids for those who tolerate them, antioxidants, and a skin barrier that isn’t assaulted every night. They’re the same things I wrote about when discussing skin longevity, and that’s no coincidence: beneath the two new terms lies the same old answer.

Supplements: where the evidence diverges

We need to be precise here, because the issue is more nuanced than either side makes it sound.

Some studies report benefits of collagen supplements for skin hydration and elasticity. However, there is also a finding worth considering: a meta-analysis published in The American Journal of Medicine found that studies funded by manufacturers tend to show benefits, while independent studies tend not to.

That doesn’t mean sponsored studies are false. It means conflicts of interest are a variable that should be disclosed and considered, just like sample size and study duration. In clinical practice, some positions do not recommend collagen supplements as a primary treatment for skin aging.

My position is simple: if a supplement makes you feel good and you can afford it, I won’t tell you to stop. But I wouldn’t consider it the cornerstone of a strategy, and I wouldn’t buy it instead of sunscreen.

What about collagen cosmetics?

Collagen applied to the skin doesn’t become dermal collagen. It’s a large molecule, and its main function in a formula is to hydrate and form a film: it retains water on the surface and improves how the skin feels to the touch.

It’s a real and pleasant effect, but it should be called what it is. A cosmetic can improve the skin’s appearance and perceived firmness; it doesn’t rebuild the dermal matrix from the outside. When a product promises to “replenish reserves,” it uses the banking metaphor as if it were a mechanism.

Actives that work on fibroblasts or remodeling processes are a different matter: those need to be assessed case by case, taking concentration, finished formula, and quality of evidence into account. I’ve written separately about the immediate effect rather than the structural one in immediate lifting effect.

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What I’d do if I were in my twenties

I wouldn’t buy anything with the word “banking” on the packaging. I’d do four things, and they’re free or nearly free.

  1. Wear sunscreen every day, not just in summer. It’s the only thing that acts directly on the factor that causes the most degradation.
  2. Don’t smoke, because smoking affects the same matrix through a different pathway.
  3. Don’t damage your skin barrier with constant exfoliation: chronically inflamed skin isn’t skin that builds.
  4. Get enough sleep, eat well, and keep general inflammation under control.

Then, if you have the budget and can tolerate it, a retinoid. And that’s it. It’s not a list that gets anyone excited, which is why we needed a new word to make it sound appealing.

My perspective

Collagen banking interests me because it's an almost perfect case study: a sound principle, a flawed metaphor, and a widely circulated statistic that almost nobody checks at its source.

What perplexes me isn't that things get simplified (simplifying is necessary; I do it every time I write, too). It's that once a simplification starts circulating, it stops being checked. You find that 1% a year in product descriptions written by knowledgeable people, who got it from someone else, who in turn got it from someone else.

When I come across a number that keeps cropping up throughout my industry, my reaction is now automatic: I look for where it came from. Very often, the original source says something slightly different. And that slight difference can sometimes make an enormous difference to people's skin.

Elisa Avalle, founder and CEO of LeLang Skin Care

Elisa Avalle is the founder of LeLang Skin Care, specializing in dermocosmetics at the University of Barcelona. She founded the brand in the Langhe region to serve Italian pharmacies and para-pharmacies.

Sources for this article

01   Varani J. et al., “Decreased collagen production in chronologically aged skin,” American Journal of Pathology, 168(6), 2006: approximately 75% reduction in type I procollagen in people over 80 compared with those aged 18-29
02   Meta-analysis of collagen supplements published in The American Journal of Medicine: systematic divergence between manufacturer-funded studies and independent studies
03   Clinical positions in dermatology and plastic surgery on the concept of collagen banking and collagen supplements
04   Regulation (EC) No. 1223/2009 on cosmetic products · Regulation (EU) No. 655/2013 on claims

On the site: how collagen is lost · collagen in cosmetics · immediate lifting effect