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Collagen banking e prevenzione della perdita di collagene
The Founder’s voice

Collagen banking: can you really store collagen for later?

Elisa Avalleof Elisa Avalle , founder of LeLang

6 min read

Collagen banking is the idea that you can accumulate collagen when you are young so that you have a reserve later on. The metaphor is banking: you deposit now and withdraw later.

The principle behind it is correct. The metaphor, however, describes something collagen does not do.

Dermal collagen does not work like a checking account: there is no deposit to draw from; there is an ongoing balance between synthesis and degradation. The habits you develop in your twenties really do matter, but not because they put something aside: because they reduce the damage that accelerates degradation. The difference may seem subtle, but it changes everything that makes sense to buy.

[INDICE:h2]

Elisa Avalle, founder and CEO of LeLang Skin Care

Elisa Avalle · Founder and dermocosmetics specialist

This is the case I most enjoy studying: a real scientific finding, summarized poorly once, and then repeated for twenty years until the wrong version became the one everyone knows.

Langhe, September 20, 2026

The number everyone knows and no one has verified

You will have read everywhere that you lose about 1% of your collagen every year from the age of twenty-five. It is the most widely cited figure in cosmetics, appearing in product descriptions, videos, and newspaper articles.

I went looking for the primary source, and what you find is interesting. The most solid reference study on this subject is by Varani and colleagues, published in 2006 in the American Journal of Pathology. It measures collagen production in chronologically aged skin and reports an approximately 75% reduction in type I procollagen in people over 80 compared with the 18–29 age group.

Notice the difference. The study compares two age extremes and measures an overall gap. It does not describe a linear 1% decline every year. That 1% is a popular extrapolation: someone divided a total loss by the number of years and derived an annual rate that the source itself does not state.

This is not a distinction for pedants. A linear decline suggests that every year lost is identical to the next, and therefore that there is a window to defend at all costs. A gap measured between age extremes says something different and more useful: the process is not uniform, it depends heavily on cumulative exposure, and that leaves room for intervention.

What really happens in the dermis

Collagen is the main structural protein in the dermis, produced by fibroblasts. It is constantly being remodeled: it is synthesized and degraded by enzymes in a cycle that never stops.

With age, two things change at the same time. Fibroblasts produce less, and degradation increases. Added to this is the factor that outweighs all the others: exposure to ultraviolet radiation, which activates degradative enzymes and fragments the existing matrix. I described the full mechanism in the article on how collagen is lost.

That is why the banking metaphor does not hold up. There is no warehouse; there is a construction site that is always open. What you can influence is not the amount deposited, but the speed at which the construction site is damaged.

“You do not deposit collagen. You avoid destroying it faster than necessary. It is less glamorous, and also much more achievable.”

The right principle inside the wrong metaphor

It would be unfair to dismiss collagen banking as a gimmick, because the core idea is sound: what you do at twenty-five affects the skin you will have at fifty. The literature agrees on this, and the evidence is robust.

The problem is that the label gets attached to products that have little to do with that principle. If “banking” means prevention, then the tools are the familiar ones: daily sun protection, retinoids for those who tolerate them, antioxidants, and a skin barrier that is not assaulted every night. They are the same things I wrote about when discussing skin longevity, and that is no coincidence: beneath the two new words lies the same old answer.

Supplements: where the evidence diverges

We need to be precise here, because the subject is more nuanced than either side tends to suggest.

There are studies reporting benefits from collagen supplements for skin hydration and elasticity. But there is also an observation that carries weight: a meta-analysis published in The American Journal of Medicine found that studies funded by manufacturers tend to show benefits, while independent studies tend not to.

This does not mean sponsored studies are false. It means that the conflict of interest is a variable that must be disclosed and considered, just as sample size and duration are considered. In clinical settings, some positions do not recommend collagen supplements as a primary treatment for skin aging.

My position is simple: if a supplement makes you feel good and you can afford it, I will not be the one to tell you to stop. But I would not consider it the cornerstone of a strategy, and I would not buy it instead of sunscreen.

What about collagen cosmetics?

Collagen applied to the skin does not become dermal collagen. It is a large molecule, and its function in a formula is mainly moisturizing and film-forming: it retains water on the surface and improves the skin’s feel.

This is a real and pleasant effect, but it should be called what it is. A cosmetic can improve the appearance and perceived firmness of the skin; it does not rebuild the dermal matrix from the outside. When a product promises to “replenish reserves,” it is using the banking metaphor as though it were a mechanism.

The discussion is different for active ingredients that act on fibroblasts or remodeling processes: those need to be assessed case by case, looking at concentration, finished formula, and quality of the evidence. I wrote separately about the immediate result rather than the structural one, in immediate lifting effect.

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What I would do if I were twenty

I would not buy anything with the word banking on the packaging. I would do four things, and they are free or almost free.

  1. Wear sunscreen every day, not just in summer. It is the only thing that acts directly on the factor responsible for the most degradation.
  2. Do not smoke, because smoking affects the same matrix through a different pathway.
  3. Do not assault the skin barrier with continuous exfoliation: chronically inflamed skin is not skin that builds.
  4. Sleep, eat adequately, and keep systemic inflammation under control.

Then, if there is the budget and you tolerate it, a retinoid. And that is all. It is not a list that excites anyone, which is why a new word was needed to make it appealing.

My take

Collagen banking interests me because it is an almost perfect case study: a correct principle, a wrong metaphor, and a popularized statistic that no one ever traces back to its source.

What leaves me perplexed is not that things get simplified—simplification is necessary, and I do it every time I write. It is that once the simplification enters circulation, it stops being verified. You find that 1% per year in product descriptions written by competent people who took it from someone else, who in turn had taken it from someone else.

When I come across a number repeated everywhere in my field, my reaction is automatic by now: I look for where it came from. Nine times out of ten, the original source says something slightly different. And that slightly different detail can sometimes make an enormous difference to people’s skin.

Elisa Avalle, founder and CEO of LeLang Skin Care

Elisa Avalle is the founder of LeLang Skin Care, specializing in dermocosmetics at the University of Barcelona. Formulated in the Langhe for Italian pharmacies.

Sources for this article

01 Varani J. et al., “Decreased collagen production in chronologically aged skin,” American Journal of Pathology, 168(6), 2006 — approximately 75% reduction in type I procollagen in people over 80 compared with those aged 18–29
02 Meta-analysis of collagen supplements published in The American Journal of Medicine: systematic divergence between manufacturer-funded and independent studies
03 Clinical positions in dermatology and plastic surgery on the concept of collagen banking and collagen supplements
04 Regulation (EC) No. 1223/2009 on cosmetic products · Regulation (EU) No. 655/2013 on claims

On the site: how collagen is lost · collagen in cosmetics · skin longevity · immediate lifting effect