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In the world of skincare, people often talk about skin becoming accustomed to the active ingredients contained in creams, serums, and cleansers. But is that really the case? In the list of skincare myths, this is one of the most persistent beliefs.
It is also a worrying belief, because no one wants to purchase products that are destined to lose their effectiveness. So let’s debunk it and better understand the mechanism that regulates the skin.
How the skin is structured
The skin is the largest organ in the body and consists of three overlapping layers that work in synergy: the hypodermis, dermis, and epidermis. The deepest layer, the hypodermis, is made up of adipocytes, fat cells that absorb, synthesize, and release lipids.
The dermis is the skin’s framework and contains fibroblasts, which, under hormonal control, produce collagen and elastin, the proteins that respectively provide strength and elasticity.
The epidermis is the upper layer, made up of overlapping cells that renew themselves continuously. They are connected by a hydrolipidic film consisting of a fatty component, sebum, and a watery component. This is the layer we touch every day: the stratum corneum, whose cells are by then devoid of a nucleus and gradually detach. The functioning of this structure is explored in greater detail in the guide to the skin barrier.
The skin is therefore subject to continuous changes, related to time, different stages of life — pregnancy, menopause — and external conditions such as UV rays and pollution.
What is a cosmetic product?
It may seem obvious, but sometimes it is useful to go back to the basics. As we did when discussing cosmeceuticals, let’s return to the definition.
A cosmetic product is a preparation made up of three components: functional ingredients, additives, and emollient bases. Additives help maintain the product’s shelf life and safety: antioxidants, for example, inhibit oxidation reactions triggered by oxygen and keep the formula’s conditions unchanged. On the skin, these same antioxidants counteract oxidative processes linked to aging.
Simply read the INCI to find out the ingredients in any cosmetic product. But be careful: quality does not depend only on the individual ingredients, but also on how they are formulated together. The guide to cosmetic ingredients goes into greater detail.
The skin does not become accustomed: it changes
Here is the central point. The skin does not develop a tolerance to an active ingredient and does not become immune to it: there is no biological mechanism that prevents a cosmetic product from producing its effect after a certain period of use.
What happens is different: the skin changes, and so do its needs. A product that is perfect at one stage may no longer meet the needs of the next. It has not lost its effectiveness: it has simply become less relevant.

Be careful not to confuse two situations. If a product no longer has the same effect, the skin’s needs or environmental conditions have generally changed. If, on the other hand, a product has begun to cause discomfort — tingling, redness, tightness — this is not tolerance but a sign of a compromised barrier. In that case, it is best to stop using it and simplify your routine.
How often should you update your skincare routine?
A well-designed routine supports skin renewal, promotes the bioavailability of active ingredients in the epidermal layers, and keeps the skin protected.
But sometimes changes are necessary — not because the skin has become accustomed to the products, but rather to provide it with the right active ingredient at the right time:
- When the seasons change: lighter textures in summer, richer hydration in winter. How to manage this is explained in the article on sensitive skin and seasonal changes.
- At different stages of life: with age, some processes slow down, making it useful to introduce active ingredients that support collagen and elastin synthesis, such as peptides.
- When a specific need changes: the appearance of dark spots, a period of increased reactivity, or a stressful time.
There is no need to overhaul your entire routine: simply adjust the products one at a time.
The wow effect and getting used to the way you look
There is another phenomenon worth mentioning, because it explains much of the feeling that a product “no longer works.” If it seems that your skin no longer has the wow effect it had at first, the product often has not changed: you have simply become used to seeing that result, and it is now your normal.
That is why “before and after” photos taken weeks apart are more reliable than memory. The everyday mirror does not record gradual changes.
Sometimes, we simply want to try something different, and there is nothing wrong with that. But if your routine is working and your skin is responding well, there is no reason to change it: consistency has the greatest impact on results, far more than the novelty of a product.


