What are gardenia stem cells?
Gardenia Stems is a meristematic cell culture of Gardenia jasminoides, a patented biotechnological active ingredient. The plant has a centuries-old tradition in Chinese medicine, where it is known as Zhi Zi; biotechnology has isolated and concentrated the fraction that works on collagen.
How they act on collagen
The molecule responsible is feruloyl-6-glucoside, a phenylpropanoid present in very high concentrations, alongside phytosterols, amino acids, and polysaccharides. Its special feature is that it works on three fronts at once: it reduces the release of MMP-1, the main collagenase that degrades the dermal matrix; directly inhibits the activity of the enzyme already in circulation; and stimulates the synthesis of new collagen. Protecting what is there and producing more are two different strategies, and here they coexist in the same molecule.
Which concerns it is indicated for and how to use it
It is indicated for loss of firmness and sagging wrinkles, where the problem is not only producing less collagen but also degrading more of it. It is used in serum, morning and evening. Like all active ingredients that work on fibroblasts, it requires consistency: results build over two months.
Efficacy testing and sustainability of the culture
The three mechanisms are documented by in vitro tests on human fibroblasts in an accelerated aging model, with statistically significant results for each. Cell culture deserves a separate note: compared with traditional cultivation, it drastically reduces water consumption, takes up negligible space, and uses no pesticides, making it possible to work with rare species without harvesting them from the wild.
Frequently asked questions
Which molecule activates gardenia stem cells?
Feruloyl-6-glucoside, a phenylpropanoid present in very high concentrations, alongside phytosterols, amino acids, and polysaccharides. It acts on three fronts at once.
What is the efficacy data for gardenia stem cells based on?
The three mechanisms are documented by in vitro tests on human fibroblasts in an accelerated aging model, with statistically significant results for each.
Why is cell culture more sustainable?
Compared with traditional cultivation, it drastically reduces water consumption, takes up negligible space, and uses no pesticides. It also makes it possible to work with rare species without harvesting them from the wild.
What is Zhi Zi?
It is the name by which gardenia is known in Chinese tradition, where it has a centuries-old history.
The selection of ingredients is curated by Elisa Avalle, founder of LeLang and a dermocosmetics specialist. Each formula is created and developed in LeLang laboratories.