The Matrixyl® 3000 is a complex of two peptides: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. It belongs to the family of signal peptides, which communicate with dermal cells, and is among the most extensively studied peptide complexes in anti-aging cosmetics.
The two fragments mimic those naturally produced by the skin when collagen breaks down. fibroblasts read them as a repair signal and respond by increasing the synthesis of collagen and glycosaminoglycans, the molecules that retain water in the dermal matrix. Palmitoyl Tetrapeptide-7 also affects the production of interleukin-6, one of the cytokines involved in the low-grade inflammation that accompanies skin aging. Two mechanisms working together: more building on one side, less degradation on the other.
It works on wrinkles caused by loss of support and on the overall firmness of the face. Apply it morning and evening before moisturizer; it is one of the best-tolerated peptides and is also suitable for reactive skin. Visible changes appear after six to eight weeks of consistent use: this is an active ingredient that rewards consistency.
It performs best when incorporated into a routine that supports its action: apply it before moisturizer, which helps retain its hydration, and combine it with daily sun protection, because the collagen that is built should be protected from what degrades it. It is one of the peptides best suited to long-term use.
On our blog, you can find an in-depth article about how Matrixyl acts on collagen in the skin and which active ingredients it pairs with.